“It is the alchemist of biochemistry.”
The Biochemical Basis of Belief: Reward Mechanism and Neuroplasticity
As Dr. Joe Dispenza and many other researchers have shown, the feeling of trust activates reward systems in the brain. This process manifests through the release of neurohormones such as dopamine, endorphins, and oxytocin. The placebo effect is therefore not merely a psychological form of “self-deception”; rather, it is the activation of the brain’s epigenetic and neuroplastic capacities. Belief rewires neural networks; however, this restructuring cannot be explained solely by epigenetic codes.
The Cryptographic Role of the Inner Voice: The Alchemy of Sound
As I emphasized in my previous articles, thought is not only biochemical, but also sound-based. The brain’s inner voice operates not at a sensory level but at a cryptographic level. Microsecond delays between neurons cause the replicated inner voice to always lag slightly behind perception. This shows that perception is not directed by words; rather, perception is first encrypted in a neural wave form, and meaning is decoded later through sound.
Therefore, in placebo and nocebo effects, the true determinant is the individual’s inner voice. Words are only surface expressions; the real power lies in how thought is internally encoded with sound. This cryptographic structure of sound directs brain waves and, when combined with awareness, creates biochemical alchemy.
Belief, Thought, and Awareness
The common feature of placebo and nocebo mechanisms is the controllability of thought. To notice one’s thoughts and consciously direct them triggers positive or negative biochemical processes. The essence of the subjective is this: to control what you think is awareness. Belief here is not just a concept but a biological reality; awareness is the key that directs this belief.
Negative belief (nocebo), when combined with emotions such as fear, anxiety, and hopelessness, increases stress hormones like cortisol. Positive belief (placebo), on the other hand, activates reward mechanisms in the brain and supports healing processes. In this context, belief can bring both healing and destruction depending on its direction. What determines this is not only external conditions but how a person uses their inner voice.
Epigenetics, Neuroplasticity, and the Unity of Sound
Epigenetic mechanisms enable genes to turn on and off in response to environmental conditions, while neuroplasticity refers to the restructuring of neural networks. However, these two processes alone do not produce meaning. Sound, that is, the cryptographic encoding of inner words, is the missing link that determines the direction of perception. Therefore, placebo and nocebo effects are as much biological as they are semiotic phenomena; they represent the transformation of meaning into biology and biology into meaning.
Conclusion: Belief Is an Alchemy
Placebo and nocebo are modern science’s rediscovery of an ancient truth: when a person changes the meaning of their inner voice, they change the chemistry of their body. When belief, awareness, and the cryptographic structure of sound unite, inner alchemy emerges. This alchemy can be healing when directed by conscious thought; or destructive when unconscious and driven by fear.
Thus, the future of modern medicine lies not only in drugs but in the understanding of the thought–sound–belief triad. When humans learn to manage their inner voice, they can consciously turn placebo and nocebo effects into a biological tool.
E.G
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